SMARCB1 Antibody

SKU: orb1410194

Description

Mouse monoclonal antibody to INI-1

Research Area

Cell Biology, Epigenetics & Chromatin

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: rSMARCB1/4588
• Immunogen: Recombinant fragment of mouse BAF47 protein (around aa257-359) (exact sequence is proprietary)
• Target: SMARCB1
• Source/Expression System: HEK293 cells
• Molecular Weight: 47kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BRG1-associated factor 47 (BAF47); hSNF5; Malignant rhabdoid tumor suppressor; RDT; RTPS1; Sfh1p; Snr1; Sucrose nonfermenting yeast homolog like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI10; Transcription factor TYE4; Transcription regulatory protein SNF5

Formalin-fixed, paraffin-embedded human epithelioid sarcoma stained with INI-1 Recombinant Mouse Monoclonal Antibody (rSMARCB1/4588). Note loss of nuclear expression in tumor cells and retained positivity in normal cells.

Formalin-fixed, paraffin-embedded human Ewing sarcoma stained with INI-1 Recombinant Mouse Monoclonal Antibody (rSMARCB1/4588). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Quick Database Links

Gene Symbol

SMARCB1

UniProt

Q12824