PPARα/δ agonist 3

SKU: orb2944725

Description

Compound 8 is a potent, orally bioavailable pan-PPAR agonist with EC50 values of 5.6 nM (PPARα), 3.4 nM (PPARδ), and 1278 nM (PPARγ). It demonstrates anti-cholestatic efficacy in vivo using ANIT- and CDCA-induced mouse models, supporting research into metabolic and liver diseases.

Research Area

Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

CAS Number	3050611-33-8
MW	450.451
Formula	C₂₃H₂₅F₃N₂O₄
SMILES	O=C(O)C(OC=1C(=CC(=CC1C)CN2C(=O)N(C3=CC=C(C=C3)C(F)(F)F)CC2)C)(C)C
Target	PPAR

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

173640845 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols