PonatiLink-1-24

SKU: orb1943345

Description

Ponatinib (PonatiLink-1-24) is a potent and selective ABL tyrosine kinase inhibitor. It is widely used in biochemical and cellular research to study BCR-ABL-driven leukemias, including in vitro assays and in vivo xenograft models for investigating resistance mechanisms.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2941512-45-2
• MW: 2120.73
• Formula: C₁₀₁H₁₄₄ClF₅N₁₂O₂₉
• SMILES: O=C(NC1=CC=C(OC(F)(F)Cl)C=C1)C=2C=NC(=C(C2)C3=NNC=C3)N4CCC(C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N5CCN(CC6=CC=C(C=C6C(F)(F)F)NC(=O)C7=CC=C(C(C#CC8=CN=C9C=CC=NN89)=C7)C)CC5)CC4
• Target: Others,Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168679888