PhiKan 083 hydrochloride

SKU: orb1706795

Description

PhiKan 083 hydrochloride is a carbazole-based small molecule that binds and stabilizes the p53 Y220C mutant surface cavity with a Kd of 167 µM, and exhibits a similar binding affinity (Kd: 150 µM) in Ln229 glioblastoma cells. This compound serves as a research tool for studying p53 reactivation in cancer biology, applicable in both biochemical and cellular assays.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	1050480-30-2
MW	274.79
Formula	C₁₆H₁₉ClN₂
SMILES	Cl.CCn1c2ccccc2c2cc(CNC)ccc12
Target	MDM-2/p53,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

16255105 ↗

Key Properties

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No computed properties available.

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