PF-4348235 HCl

SKU: orb2283870

Description

PF-4348235 HCl is a dual-action MABA compound, functioning as a potent M3 muscarinic receptor antagonist (Ki: 0.73 nM) and a β2-adrenoceptor agonist (EC50: 3.7 nM). It serves as a research bronchodilator for investigating therapeutic strategies in respiratory diseases like COPD, utilizing both in vitro binding assays and in vivo preclinical models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Adrenergic Receptor,AChR
• Molecular Weight: 753.78
• Purity: 98.81%
• Formula: C₃₆H₅₀Cl₂N₄O₇S
• SMILES: O[C@H](C1=CC(NS(C)(=O)=O)=C(C=C1)O)CNCCCCCCCCCN(CC2)CCC2OC(NC3=C(C4=CC(Cl)=C(C=C4)O)C=CC=C3)=O.Cl

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

M3 mAChR, AdrenergicReceptor, Adrenergic Receptor, PF-4348235 HCl(1017857-38-3 Free base), β2AR/M-receptor agonist-2 HCl, β2AR/Mreceptoragonist2HCl(1017857383Freebase), β2-adrenergic receptor

Compound Identifiers

PubChem CID

172005544