Petosemtamab Antibody

SKU: orb1980554

Description

Petosemtamab (MCLA-158) is a potent bispecific antibody targeting EGFR and LGR5, disrupting oncogenic signaling and inducing receptor degradation. It is utilized in preclinical research for solid tumors, including head and neck squamous cell carcinoma and colorectal cancer, with studies demonstrating activity in both in vitro and in vivo models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	EGFR
Molecular Weight	145.97 kDa
Purity	>95% (May vary between batches)
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	6.98 mg/mL
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Petosemtamab, MCLA 158, MCLA158, MCLA-158, EGFR

Quality Guarantee

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Gene Symbol

EGFR

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