Persicogenin

SKU: orb1297248

Description

Persicogenin is a bioactive small molecule with reported anticancer, antimutagenic, and antileishmanial properties. In vitro studies demonstrate its ability to inhibit mouse tsFT210 cancer cell proliferation by inducing a dose-dependent G2/M phase cell cycle arrest, supporting its use in oncology and parasitology research.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 28590-40-1
• MW: 316.31
• Purity: 98.49% (May vary between batches)
• Formula: C₁₇H₁₆O₆
• SMILES: COc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccc(OC)c(O)c1
• Target: Anti-infection
• Solubility: DMSO:60 mg/mL (189.69 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.16 mM)

Bioactivity

• In Vitro:
  Compound 1 exhibited moderate antimycobacterial activity against Mycobacterium tuberculosis with the MIC value of 174.8 microM, whereas compounds 4, 7, and 8 exhibited weak activity with the MIC values of 606.0, 704.2 and 699.3 microM respectively. Compound 7 showed moderate cytotoxicity against human small cell lung cancer (NCI-H187) cells with the MIC value of 24.6 microM, whereas compound 8 exhibited moderate toxicity against NCI-H187 cells and week toxicity against human breast cancer (BC) cells with the MIC values of 19.2 and 38.4 microM respectively

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Persicogenin, inhibit, Inhibitor, Hesperetin-7-methyl ether, Anti-infection, Antiinfection, Antifection

Compound Identifiers

PubChem CID

14157910