PDCD1 Antibody / PD-1 / PD1

• Catalog Number: orb386225
• Category: Antibodies
• Description: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
• Clonality: Recombinant
• Species/Host: Rabbit
• Isotype: Rabbit IgG, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: A partial length human protein was used as the immunogen for the recombinant PD1 antibody.
• UniProt ID: Q15116
• Tested applications: IHC-P
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Application notes: Titering of the recombinant PD1 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
• Antibody Type: Primary Antibody
• Clone Number: PDCD1/1410R
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Research Area: Apoptotic, Cancer, Epigenetics, Immunology, Neuros
• Note: For research use only

IHC testing of FFPE human tonsil with recombinant PD1 antibody (clone PDCD1/1410R). Required HIER: steam sections in 10 mM Tris with 1 mM EDTA, pH9, for 10-20 min.

SDS-PAGE analysis of purified, BSA-free recombinant PD1 antibody (clone PDCD1/1410R) as confirmation of integrity and purity.