NRP1 (N) Antibody, Rabbit Polyclonal

SKU: orb131834

Description

Rabbit polyclonal to NRP1. Neuropilin-1 (NRP1) is one of two neuropilins containing specific protein domains, which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for NRP1.

Research Area

Cancer, Developmental Biology, Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human NRP1.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human NRP1
• Molecular Weight: 103
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Neuropilin-1 antibody, anti Vascular endothelial cell growth factor 165 receptor antibody, anti CD304 antibody, anti NRP antibody, anti VEGF165R antibody

Western blot analysis of total cell extracts from human Jurkat, using NRP1 antibody

Quick Database Links

UniProt

O14786