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Moexiprilat

SKU: orb1980037

Description

Moexiprilat is the active metabolite of the prodrug moexipril, functioning as a potent ACE inhibitor (IC50 = 2.1 nM). It inhibits angiotensin II- and estrone-stimulated cardiac fibroblast proliferation in vitro and reduces blood pressure in hypertensive ovariectomized mouse models in vivo.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number103775-14-0
MW470.51
FormulaC25H30N2O7
SMILESC[C@H](N[C@H](C(O)=O)CCC1=CC=CC=C1)C(N2CC3=CC(OC)=C(OC)C=C3C[C@H]2C(O)=O)=O
TargetOthers,Angiotensin-converting Enzyme (ACE)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Moexiprilat (orb1980037)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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