ML-178

SKU: orb1306095

Description

ML-178 is a potent and selective S1PR4 agonist with an EC50 of 46 nM, showing no activity against other S1P receptors at 25 µM. This tool compound is valuable for investigating S1PR4-specific signaling in immunological and inflammatory processes, both in cellular assays and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1355026-47-9
• MW: 441.93
• Purity: 96.14% (May vary between batches)
• Formula: C₁₃H₉Br₂Cl₂NO₂
• SMILES: Clc1ccc(OCCOc2ccc(Br)nc2Br)c(Cl)c1
• Target: Others,LPL Receptor
• Solubility: DMSO:15 mg/mL (33.94 mM)

Bioactivity

• Target IC50:
  S1P4 receptor:46 nM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

autoimmune diseases, CYM50179, CYM-50179, CYM 50179, Inhibitor, hrombocytopenia, inhibit, LPL Receptor, ML178, ML-178, ML 178, Lysophospholipid Receptor, viral infections

Compound Identifiers

PubChem CID

44620892