Lorigerlimab

• Catalog Number: orb1980375
• Category: Antibodies
• Description: Lorigerlimab (MGD019) is a bispecific IgG4 dual-affinity re-targeting (DART) antibody that inhibits PD-1 and CTLA-4 to enhance T-cell responses, currently being investigated for metastatic castration-resistant prostate cancer (mCRPC) [1] [2] [3].
• CAS Number: 2416595-46-3
• Purity: 98.00%
• Conjugation: Unconjugated
• Target: Lorigerlimab
• Biological Activity: Lorigerlimab (MGD019) is a bispecific IgG4 dual-affinity re-targeting (DART) antibody that blocks both PD-1 and CTLA-4, enhancing T-cell responses. It is under investigation for the treatment of metastatic castration-resistant prostate cancer (mCRPC) [1] [2] [3].
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.