Laduviglusib dihydrochloride

SKU: orb2565890

Description

Laduviglusib (CHIR99021) is a potent and selective GSK-3 inhibitor with the formula C₂₂H₁₈ClN₅O. It is widely used in research to investigate GSK-3's role in stem cell biology, metabolic disorders, and neurodegenerative diseases, employing both in vitro and in vivo experimental models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2109414-84-6
• MW: 538.26
• Formula: C₂₂H₂₀Cl₄N₈
• SMILES: ClC1=C(C=2C(=CN=C(NCCNC3=CC=C(C#N)C=N3)N2)C=4NC(C)=CN4)C=CC(Cl)=C1.Cl.Cl
• Target: GSK-3,Wnt/beta-catenin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91826519