Kynurenic acid

SKU: orb1980161

Description

Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonvulsant properties. It has neuroprotective and anticonvulsant properties and can be used to study neurodegeneration and metabolism-related diseases.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 492-27-3
• MW: 189.17
• Purity: 99.69%
• Formula: C₁₀H₇NO₃
• SMILES: OC(=O)C1=CC(O)=C2C=CC=CC2=N1
• Target: GPCR,iGluR,NMDAR,GluR,Endogenous Metabolite,Apoptosis,CXCR
• Solubility: H2O:<0.1 mg/mL (insoluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.29 mM);DMSO:7.76 mg/mL (41.02 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

GPR35, Glutamate receptor, Fibrostop 2, NMDA receptor, Quinurenic acid

Compound Identifiers

PubChem CID

3845