KNI-1657

SKU: orb1987163

Description

KNI-1657 is a highly potent and selective HIV-1 protease inhibitor, demonstrating significant activity against the pNL4-3 strain with an EC50 of 3 nM. It is particularly effective against lopinavir-resistant HIV-1 variants, making it a valuable tool for antiviral research in both in vitro enzyme inhibition and cell-based assays.

Key Properties

• MW: 756.92
• Formula: C₄₁H₄₈N₄O₈S
• SMILES: O=C([C@H]1N(C([C@@H](O)[C@@H](NC([C@@H](NC(C2=CC3=CC=CC(OC)=C3O2)=O)[C@@H]4COCC4)=O)CC5=CC=CC=C5)=O)CSC1(C)C)NCC6=C(C)C=CC=C6C
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129909612