Imidacloprid-urea

SKU: orb1745147

Description

Imidacloprid-urea is a key environmental metabolite of the neonicotinoid insecticide imidacloprid. It is used in environmental fate studies to investigate soil adsorption dynamics, as it can compete with the parent compound for binding sites, influencing imidacloprid's persistence and mobility.

Research Area

Metabolism Research

Key Properties

• CAS Number: 120868-66-8
• MW: 211.65
• Purity: 99.96%
• Formula: C₉H₁₀ClN₃O
• SMILES: C(N1C(=O)NCC1)C=2C=CC(Cl)=NC2
• Target: Drug Metabolite
• Solubility: H2O:11.2 mg/mL (52.92 mM);DMSO:112.5 mg/mL (531.54 mM)

Bioactivity

• In Vivo:
  Imidacloprid(0, 5, 10, 20 mg/kg/day ; oral ; female rats) shows mild pathological changes in the brain, liver, and kidneys of rats.
• In Vitro:
  Imidacloprid (0, 10, and 20 μM ; 4-6 days) can reduce insulin-stimulated glucose uptake in adipocytes (3T3-L1), hepatocytes (HepG2), and myotubes (C2C12) cell culture models. Treatment with imidacloprid inhibits phosphorylation of protein kinase B (AKT) and ribosomal S6 kinase (S6K).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, DrugMetabolite

Compound Identifiers

PubChem CID

15390532