IL18 Antibody

SKU: orb2309942

Description

IL18 Antibody

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Images & Validation

• Tested Applications: IHC
• Reactivity: Canine, Equine, Feline, Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2
• Clone No.: IL18/4624
• Immunogen: Recombinant fragment (around aa1-193) of human IL-18 protein (exact sequence is proprietary)
• Target: IL18
• Source/Expression System: Bioreactor
• Molecular Weight: 18kDa
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

Iboctadekin; IFN gamma inducing factor; IGIF; IL1 gamma; IL18; IL18 protein; IL1F4; IL1g; IL1gamma; Interleukin 18; Interleukin-1 gamma; MGC12320

Analysis of Protein Array containing more than 19000 full-length human proteins using IL-6-Monospecific Mouse Monoclonal Antibody (IL18/4624). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human kidney stained with IL-6 Mouse Monoclonal Antibody (IL18/4624) at 2 ug/ml. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human pancreas stained with IL-6 Mouse Monoclonal Antibody (IL18/4624) at 2 ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

SDS-PAGE Analysis of Purified IL-6 Mouse Monoclonal Antibody (IL18/4624). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

IL18

UniProt

Q14116