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IC-8
Catalog Number: orb1785882
Product Properties
| Catalog Number | orb1785882 |
|---|---|
| Category | Small Molecules |
| Description | IC8 is an ionizable cationic lipid. It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs). Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and Omicron variants in mice.1 Administration of mRNA encoding B7-H3 X CD3 bispecific T cell engaging (BiTE) antibodies in IC8-containing LNPs reduces tumor growth in MV4-11 and A375 mouse xenograft models. |
| MW | 1049.8 |
| CAS Number | 2349307-32-8 |
| Formula | C66H136N4O4 |
| SMILES | OC(CCCCCCCCCCCC)CN(CC(CCCCCCCCCCCC)O)CCCN1CCN(CCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)CC1 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Chemical structure of orb1785882
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