Halofuginone hydrochloride

SKU: orb2283776

Description

Halofuginone hydrochloride is a potent, 18.3 nM Ki competitive inhibitor of prolyl-tRNA synthetase. It is widely used in research for its anti-fibrotic, anti-inflammatory, and anti-cancer properties, with applications in studying TGF-β signaling, collagen synthesis, and pulmonary hypertension in both in vitro and in vivo models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1217623-74-9
• MW: 451.14
• Formula: C₁₆H₁₈BrCl₂N₃O₃
• SMILES: Cl.OC1CCCN[C@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O
• Target: Others,Parasite,TGF-beta/Smad,Sodium Channel,Calcium Channel,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46781676