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GSK-3β inhibitor 15

SKU: orb2278340

Description

This potent and selective GSK-3β inhibitor (IC50 = 3.4 nM) reduces Aβ 1-42-induced tau phosphorylation and LPS-induced iNOS expression in vitro. It offers neuroprotection against Aβ-mediated toxicity, making it a valuable chemical probe for Alzheimer's disease research in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW352.41
FormulaC17H16N6OS
TargetApoptosis,Others,GSK-3,Microtubule Associated

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

GSK-3β inhibitor 15 (orb2278340)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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