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GNF-351
Catalog Number: orb746446
Product Properties
| Catalog Number | orb746446 |
|---|---|
| Category | Small Molecules |
| Description | GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential; antagonizes agonist and SAhRM-mediated suppression of SAA1, inhibit both DRE-dependent and -independent activity; decreases migration and invasion of HNSCC cells and prevents benzo[a]pyrene-mediated induction of the chemotherapy efflux protein ABCG2. |
| MW | 411.5 |
| Formula | C24H25N7 |
| SMILES | N1C2C(=NC(C3=CC(C)=CN=C3)=NC=2NCCC2C3=C(N=C2)C=CC=C3)N(C(C)C)C1 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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