GNE-0946

SKU: orb1707261

Description

GNE-0946 is a potent and selective RORγ agonist with an EC50 of 4 nM in HEK-293 cells. This small molecule is a valuable research tool for studying Th17 cell biology, autoimmune diseases, and cancer immunotherapy in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1677667-24-1
• MW: 460.79
• Purity: 98.11% (May vary between batches)
• Formula: C₂₂H₁₂ClF₃N₂O₄
• SMILES: O=C(O)C=1C=CC(=CC1O)C=2N=C(C(=O)C=3C(Cl)=CC=CC3C(F)(F)F)N4C=CC=CC24
• Target: ROR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91664317