GB-110 hydrochloride (1252806-70-4 free base)

SKU: orb1709634

Description

GB-110 hydrochloride is a potent, orally bioavailable, non-peptidic agonist of protease-activated receptor 2 (PAR2). It selectively triggers PAR2-mediated intracellular calcium release in HT29 cells with an EC50 of 0.28 µM. This tool compound is used in vitro and in vivo to investigate PAR2's role in inflammation, pain, and cancer research.

Images & Validation

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Key Properties

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MW	645.23
Formula	C₃₃H₄₉ClN₆O₅
SMILES	O=C(C1=CC=NO1)N[C@@H](CC2CCCCC2)C(N[C@@H]([C@@H](C)CC)C(NCC3=CC=CC(C(N4CCC(CN)CC4)=O)=C3)=O)=O.Cl
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

139600279 ↗

Key Properties

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No computed properties available.

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