Framycetin sulfate

SKU: orb1306492

Description

Framycetin sulfate, also known as Neomycin Sulphate B, is an aminoglycoside antibiotic characterized by its structure of linked aminosugars. It is widely used in research for studying bacterial protein synthesis inhibition and is applied in both in vitro microbiological assays and in vivo models of topical infection.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 4146-30-9
• MW: 908.86
• Purity: 99.89%
• Formula: C₂₃H₅₂N₆O₂₅S₃
• SMILES: OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.[H][C@@]1(O[C@@H]2[C@@H](O)[C@H](N)C[C@H](N)[C@@]2([H])O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2N)O[C@H](CO)[C@@H](O[C@@]2([H])O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]2N)[C@H]1O
• Target: Antibacterial,Antibiotic
• Solubility: H2O:250 mg/mL (275.07 mM);DMSO:Insoluble

Bioactivity

• Target IC50:
  Hammerhead ribozyme:13.5 μM (Ki)|RNase P cleavage activity:35 μM (Ki)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cleavage, E.coli, Drosha, divalent, Bacterial, Antibiotic, 5″-azido, ion, inhibit, metal, Neomycin B, Neomycin Sulphate B, neomycin, miR-525, Framycetin, Fradiomycin B, Framycetin sulfate, Framycetin Sulfate, Framycetin sulphate, encephalopathy, hammerhead, hepatic, Inhibitor, RNase, ribozyme

Compound Identifiers

PubChem CID

24978553