Dihydrodaidzein

SKU: orb1297395

Description

This product, (±)-Dihydrodaidzein, is a key intermediate in the microbial metabolism of soy isoflavones. Its study is crucial for elucidating the pathways and regulatory mechanisms underlying the bacterial production of equol in gut microbiota, relevant for in vitro fermentation models and metabolic research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 17238-05-0
• MW: 256.25
• Purity: 99.30% (May vary between batches)
• Formula: C₁₅H₁₂O₄
• SMILES: Oc1ccc(cc1)C1COc2cc(O)ccc2C1=O
• Target: Endogenous Metabolite
• Solubility: DMSO:250 mg/mL (975.61 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.61 mM)

Bioactivity

• In Vitro:
  Recently, we isolated a Dihydrodaidzein (DHD)-producing Clostridium-like bacterium, strain TM-40, from human feces. We investigated the effects of strain TM-40 on in vitro daidzein metabolism by human fecal microbiota from a male equol producer and two male equol non-producers. In the fecal suspension from the male equol non-producer and DHD producer, DHD was detected in the in vitro fecal incubation of daidzein after addition of TM-40. The DHD concentration increased as the concentration of strain TM-40 increased. In the fecal suspension from the equol producer, the fecal equol production was increased by the addition of strain TM-40. The occupation ratios of Bifidobacterium and Lactobacillales were higher in the equol non-producers than in the equol producer. Adding isoflavone-metabolizing bacteria to the fecal microbiota should facilitate the estimation of the metabolism of isoflavonoids by fecal microbiota

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(±)-Dihydrodaidzein, Dihydrodaidzein, EndogenousMetabolite, Endogenous Metabolite, Inhibitor, inhibit, P-gp

Compound Identifiers

PubChem CID

176907