Dicentrine

SKU: orb1684647

Description

Dicentrine, the primary alkaloid from Ocotea puberula leaves, is an α1-adrenoceptor antagonist. Its activity, confirmed via [3H]prazosin binding and in vitro tension assays, supports research into benign prostatic hyperplasia (BPH) and related urological disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 517-66-8
• MW: 339.39
• Purity: 99.99%
• Formula: C₂₀H₂₁NO₄
• SMILES: CN1[C@@]2(C=3C(C=4C(C2)=CC(OC)=C(OC)C4)=C5C(=CC3CC1)OCO5)[H]
• Target: Adrenergic Receptor
• Solubility: DMSO:8 mg/mL (23.57 mM)

Bioactivity

• In Vitro:
  Dicentrine combined with TNF-α treatment at concentrations of 25, 30, and 40 μM significantly reduced the survival rate of A549 cells (54.85%, 54.35%, and 45.15%, respectively), demonstrating a more pronounced effect compared to Dicentrine alone .

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dicentrine

Compound Identifiers

PubChem CID

101300