Demethylzeylasteral

SKU: orb1304219

Description

Demethylzeylasteral (T-96) is a bioactive natural product with demonstrated anti-inflammatory, immunosuppressive, and anti-tumor properties. Research indicates it blocks TGF-β signaling to inhibit triple-negative breast cancer cell invasion and shows efficacy in reducing atherosclerosis in experimental models.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 107316-88-1
• MW: 480.59
• Purity: >99.99% (May vary between batches)
• Formula: C₂₉H₃₆O₆
• SMILES: [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC(=O)c4c(C=O)c(O)c(O)cc4[C@]3(C)CC[C@@]21C)C(O)=O
• Target: FAK,UGT,NF-κB,Apoptosis,Estrogen Receptor/ERR,TGF-beta/Smad
• Solubility: DMSO:87 mg/mL (181.03 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.87 mM)

Bioactivity

• Target IC50:
  UGT1A6:0.6 μM(Ki)|UGT2B7:17.3 μM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

T96, T-96, T 96, UGT1A6, UGT2B7, Inhibitor, inhibit, Apoptosis, Demethylzeylasteral, Demethylzeylasteral (T-96)

Compound Identifiers

PubChem CID

10322911