Daurisoline

SKU: orb1304584

Description

Daurisoline, the (R,R)-enantiomer, is a bisbenzylisoquinoline alkaloid that acts as a hERG channel inhibitor and an autophagy blocker. It is utilized in cardiovascular safety pharmacology research and in vitro studies investigating autophagy pathways and related diseases.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 70553-76-3
• MW: 610.74
• Purity: 99.96% (May vary between batches)
• Formula: C₃₇H₄₂N₂O₆
• SMILES: COc1cc2CCN(C)[C@H](Cc3ccc(O)c(Oc4ccc(C[C@H]5N(C)CCc6cc(OC)c(OC)cc56)cc4)c3)c2cc1O
• Target: Autophagy,Potassium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.64 mM);DMSO:242.5 mg/mL (397.06 mM)

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, (R,R)-Daurisoline, Daurisoline, PotassiumChannel, Potassium Channel

Compound Identifiers

PubChem CID

51106