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CRBN modulator-1

SKU: orb1298606

Description

WUN29654 is a thalidomide-based CRBN modulator with a Ki of 0.98 µM and an IC50 of 3.5 µM. This small molecule is used in biochemical and cellular research to study targeted protein degradation and probe CRBN-dependent pathways in vitro.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2407829-65-4
MW324.29
Purity99.36%
FormulaC17H12N2O5
SMILESOc1cc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c3cccc(c1)c23
TargetLigand for E3 Ligase
SolubilityDMSO:3.25 mg/mL (10.02 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

CRBN modulator 1, CRBN modulator1, CRBN modulator-1, E3 ligase-recruiting Moiety, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, inhibit, Inhibitor, WUN 29654, WUN29654, WUN-29654

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Key Properties

No computed properties available.

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Protocol Information

CRBN modulator-1 (orb1298606)

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Available Sizes

Select a size below

500 mg
1 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 120.00
5 mg
$ 120.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 510.00