Cholic acid sodium hydrate

SKU: orb1982004

Description

Cholic acid sodium hydrate is a primary bile acid that facilitates fat absorption and cholesterol excretion. It is widely used in research on lipid metabolism, digestive physiology, and as a critical reagent for in vitro studies of bile acid transporters and nuclear receptor signaling (e.g., FXR).

Research Area

Metabolism Research

Key Properties

• CAS Number: 206986-87-0
• MW: 448.57
• Purity: 99.88%
• Formula: C₂₄H₄₁NaO₆
• SMILES: O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC([O-])=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C.[Na+].O xH2O
• Target: Endogenous Metabolite

Bioactivity

• In Vivo:
  Cholic acid sodium hydrate (1% cholic acid supplemented diet, oral, 14 days) may reduce SHP (small heterodimer partner) protein expression via upregulation of miR142-3p.
• In Vitro:
  Cholic acid sodium hydrate (1 mg/mL, 30 minutes) competitively binds to Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23679061