Cefepime Dihydrochloride Monohydrate

SKU: orb1226724

Description

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria. (In Vitro):Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics.(In Vivo):Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin and skin structure infections. Cefepime is generally well tolerated.

Key Properties

• CAS Number: 123171-59-5
• MW: 571.5
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₄N₆O₅S₂·2HCl·H₂O
• SMILES: C[N+]1(CCCC1)CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O.O.Cl.[Cl-]
• Target: Antibacterial
• Solubility: Soluble in DMSO

Bioactivity

• In Vivo:
  Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin and skin structure infections. Cefepime is generally well tolerated.
• In Vitro:
  Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cefepime Hydrochloride | Cefepime HCl | Cefepime hydrochloride monohydrate

Quick Database Links

Gene Symbol

Antibacterial