Cediranib maleate

SKU: orb1702614

Description

Cediranib maleate (AZD2171 maleate) is an orally bioavailable, potent inhibitor targeting VEGFR2 and other key tyrosine kinases like PDGFR and c-Kit. It has been studied in ovarian cancer models, where it demonstrates anti-angiogenic activity and can upregulate MHC-I expression through transcriptional mechanisms in both in vitro and in vivo settings.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 857036-77-2
• MW: 566.58
• Formula: C₂₉H₃₁FN₄O₇
• SMILES: C(=C\C(O)=O)\C(O)=O.O(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=CN1)C=4C(F)=C5C(=CC4)NC(C)=C5
• Target: PDGFR,Autophagy,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11226834