Bat SARS-like coronavirus WIV1 Spike Trimer Protein (R668A, KV969-970PP), His Tag

SKU: orb2999577

Description

The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.4 kDa. The protein migrates as 160-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: Spike protein
• Reactivity: Virus
• Tag: C-10×His
• Molecular Weight: 136.4 kDa
• Expression Region: Tyr 15 - Pro 1196
• Purity: 90%
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Form/Appearance: Powder
• Buffer/Preservatives: 0.1 M Sodium citrate, pH 5.5
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Spike protein

UniProt

AGZ48828.1 (R668A, KV969-970PP)

RefSeq:AGZ48828.1, KV969, 970, R668