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| Catalog Number | orb1951033 |
|---|---|
| Category | Antibodies |
| Description | Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Atg16L1 |
| UniProt ID | Q676U5 |
| Tested applications | IHC, WB |
| Dilution range | WB 1:500~1:2000 IHC 1:50~1:200 |
| Antibody Type | Recombinant Antibody |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | APG16 like 1; APG16L; APG16L beta; ATG16A; ATG16L; Read more... |
| Note | For research use only |
![Atg16L1 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951033_1.png)
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
![Atg16L1 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951033_2.png)
Western blot analysis of Atg16L1 expression in HeLa cell lysate.
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