AR-08

SKU: orb1710625

Description

AR-08 is a selective α2-adrenergic receptor agonist utilized in neuroscience research, particularly for investigating attention deficit disorders. It is employed in both in vitro binding assays and in vivo animal models to study receptor function and potential therapeutic mechanisms.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 226081-74-9
• MW: 240.26
• Purity: 99.70% (May vary between batches)
• Formula: C₁₂H₁₂N₆
• SMILES: N#CC=1C=C(NC2=NCCN2)C(=C3N=CNC13)C
• Target: Adrenergic Receptor

Bioactivity

• In Vivo:
  After intravenous administration of a single dose of 15 mg/kg to 6 healthy lactating goats, the pharmacokinetic behavior of Ibafloxacin is studied. Plasma concentrations of Ibafloxacin are determined by high-performance liquid chromatography with fluorescence detection. Following intravenous injection, Ibafloxacin exhibits very rapid initial distribution, with a mean half-life of 0.35 h, followed by slower elimination, with a mean half-life of 3.76 h. The elimination half-life of Ibafloxacin after oral administration has been reported to be 3.83 h in dogs and 3.00 h in cats.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AdrenergicReceptor, Adrenergic Receptor, AR08, AR-08, AR 08, α2 adrenergic receptor

Compound Identifiers

PubChem CID

10220387