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APJ receptor agonist 5
Catalog Number: orb1686887
| Catalog Number | orb1686887 |
|---|---|
| Category | Small Molecules |
| Description | APJ receptor agonist 5 |
| Purity | 98.00% |
| MW | 479.52 |
| Biological Activity | APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50:0.4 nM). APJ receptor agonist 5 has excellent pharmacokinetic profiles in rodent models of heart failure (HF) and an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 can improve cardiac function and can be used in the study of HF disease. |
| CAS Number | 2135514-20-2 |
| Formula | C26H29N3O6 |
| SMILES | C(OCC)C=1N(C(O)=C(C(=O)N2C[C@H](CC2)C3=CC=CC=C3)C(=O)N1)C4=C(OC)C=CC=C4OC |
| Storage | -20°C |
| Note | For research use only |
[Pyr1]-Apelin 13 [orb1140672]
> 95% by HPLC
1533.8 Da
Glp-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
1 mg[Pyr1]-Apelin-13 [orb1219858]
> 98% (HPLC)
217082-60-5
1533.8
C69H108N22O16S
1 g, 500 mg, 200 mg, 50 mg, 100 mg, 25 mg, 5 mg, 10 mg
