Antifungal agent 137

SKU: orb3173785

Description

Antifungalagent 137 (Compound 4S) is an antifungal compound that inhibits Phomopsis sp. (PS) with an EC50 value of 0.15 μg/mL. It targets lanosterol 14α-demethylase (CYP51) with an IC50 value of 5.00 μg/mL. Additionally, it disrupts PS mycelial morphology, compromises cell membrane integrity, and increases intracellular ROS levels, inducing oxidative stress. This compound is useful for research on fungal infections.

Key Properties

• CAS Number: 3032062-22-6
• MW: 499.48
• Formula: C₂₁H₂₁F₄N₅O₃S
• SMILES: O=S(=O)(C1=CC(F)=CC=C1F)N2CCN(CC2)CC(O)(C3=CC=C(F)C=C3F)CN4N=CN=C4
• Target: Cytochromes P450,Antifungal,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Cytochromes P450,Antifungal,ROS