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Anti-RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody
Catalog Number: orb547658
| Catalog Number | orb547658 |
|---|---|
| Category | Antibodies |
| Description | Anti-RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody |
| Species/Host | Rabbit |
| Clonality | Monoclonal |
| Clone Number | AEDC-18 |
| Tested applications | FC, ICC, IF, IHC, WB |
| Reactivity | Human, Mouse, Rat |
| Isotype | Rabbit IgG |
| Immunogen | A synthesized peptide derived from human RING2 / RING1B / RNF2 E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. |
| Antibody Type | Primary Antibody |
| Concentration | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Form/Appearance | Liquid |
| Conjugation | Unconjugated |
| MW | 17 kDa |
| UniProt ID | Q99496 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | Vinculin; Metavinculin; MV; VCL Read more... |
| Note | For research use only |
| Application notes | WB 1:500-1:2000IHC 1:50-1:200ICC/IF 1:50-1:200FC 1:50. Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of RNF2 expression in HeLa cell lysate using anti-RNF2 antibody.
