CD70 Biosimilar Antibody

• Catalog Number: orb689310
• Category: Antibodies
• Description: Anti-CD70 (vorsetuzumab biosimilar) mAb
• Target: CD70
• Clonality: Monoclonal
• Species/Host: Human
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Powder
• Purification: Purified from cell culture supernatant by affinity chromatography
• UniProt ID: P32970
• Tested applications: ELISA, FC
• Dilution range: ELISA 1:5000-10000 Flow Cyt 1:100
• Application notes: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
• Antibody Type: Biosimilar Antibody
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: CD70CD27LCD27LGTNFSF7
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human CD70, mFc-His tagged protein orb689401 can bind Anti-CD70 Neutralizing antibody in a linear range of 3.91-139.9 ng/ml.

HEK293 cell line transfected with irrelevant protein (B) and human CD70 (A) were surface stained with anti-CD70 neutralizing antibody 1 μg/ml (vorsetuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Flow cytometry analysis of antigen binding of anti-human CD70 mAb (orb689310). (A) A clear peak shift of orb689310 was seen compared to the control when incubated with CD70-expressing THP1 cells, indicating strong binding of orb689310 to CD70. Antibodies were incubated at 2 μg/mL.