AMG 837 hemicalcium

SKU: orb1687195

Description

AMG 837 hemicalcium is a potent and orally bioavailable partial agonist of the GPR40 (FFA1) receptor, demonstrating high binding affinity (pIC50: 8.13). It has been shown to stimulate glucose-dependent insulin secretion in vitro and reduce blood glucose levels in rodent models, supporting its use in diabetes research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1291087-14-3
• MW: 914.954
• Formula: C₅₂H₄₀CaF₆O₆
• SMILES: CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2]
• Target: Others,GPCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124201854