AGN 205327

SKU: orb1710475

Description

AGN 205327 is a potent and selective synthetic agonist for retinoic acid receptors (RARs), with highest potency for RARγ (EC50 = 32 nM). Its selectivity over RXRs makes it a valuable research tool for studying RAR-specific signaling in cellular models and for exploring therapeutic pathways in dermatology and oncology.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 2070018-29-8
• MW: 390.47
• Purity: 99.71% (May vary between batches)
• Formula: C₂₄H₂₆N₂O₃
• SMILES: CC1(C)C=2C(=CC=C(C(=NO)C3=CC=4C(N3)=CC=C(C(O)=O)C4)C2)C(C)(C)CC1
• Target: Retinoid Receptor,Autophagy

Bioactivity

• Target IC50:
  RARα:3766 nM (EC50)|RARγ:32 nM (EC50)|RARβ:734 nM (EC50)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AGN205327, AGN-205327

Compound Identifiers

PubChem CID

138115126