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5-LOX inhibitor

SKU: orb1962274

Description

This compound, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, is a 5-lipoxygenase (5-LOX) inhibitor identified as a process-related impurity of itraconazole. It serves as a research tool for investigating the 5-LOX pathway in leukotriene biosynthesis during in vitro enzymatic and cellular assays.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number106461-41-0
MW393.48
Purity98.01% (May vary between batches)
FormulaC22H27N5O2
SMILESCCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(O)cc2)c1=O
TargetHedgehog/Smoothened,Lipoxygenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-LOX, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

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Key Properties

No computed properties available.

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5-LOX inhibitor (orb1962274)

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Available Sizes

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 170.00
100 mg
$ 230.00
500 mg
$ 520.00
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