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5-HT6 inverse agonist 1
Catalog Number: orb2814157
Product Properties
| Catalog Number | orb2814157 |
|---|---|
| Category | Small Molecules |
| Description | 5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models. |
| MW | 498.4 |
| CAS Number | 2727088-38-0 |
| Formula | C22H22Cl2FN3O3S |
| SMILES | Cl.O=C(NC1CCNCC1)C=2C=CN(C2C=3C=CC(F)=CC3)S(=O)(=O)C=4C=CC=C(Cl)C4 |
| Storage | -20°C |
| Note | For research use only |
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