2-Linoleoyl Glycerol

• Catalog Number: orb2283582
• Category: Small Molecules
• Description: 2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.
• CAS Number: 3443-82-1
• Purity: 98.00%
• MW: 354.531
• SMILES: CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC(CO)CO
• Formula: C₂₁H₃₈O₄
• Biological Activity: 2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.