2-Linoleoyl Glycerol

SKU: orb2283582

Description

2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.

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Key Properties

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CAS Number	3443-82-1
MW	354.531
Formula	C₂₁H₃₈O₄
SMILES	CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC(CO)CO
Target	Cannabinoid Receptor,Others

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Cannabinoid Receptor,Others

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