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Human VSIG4 Protein
Catalog Number: orb257931
| Catalog Number | orb257931 |
|---|---|
| Category | Proteins |
| Description | V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. |
| Reactivity | Human |
| Tag | C-7×His |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 30.1 kDa |
| Target | VSIG4 |
| Protein Sequence | AAH10525 |
| Source | Human VSIG4, His Tag (orb257931) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Pro 283 (Accession # AAH10525). |
| Expression System | HEK293 |
| Expression Region | Arg 20 - Pro 283 |
| Endotoxins | 1.0 EU per μg |
| NCBI | AAH10525 |
| Storage | -20℃ |
| Buffer/Preservatives | PBS, pH7.4 |
| Alternative names | VSIG4,CRIg,Z39IG Read more... |
| Note | For research use only |
| Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.1 kDa. The protein migrates as 37-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human VSIG4 protein
Human VSIG4 Protein, hFc Tag [orb1173745]
Unconjugated
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 55.3 kDa after removal of the signal peptide. The apparent molecular mass of VSIG4-hFc is approximately 55-70 kDa due to glycosylation.
Mammalian
10 μg, 100 μg, 50 μgHuman VSIG4 protein [orb392707]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Human cells
500 μg, 50 μg, 10 μgHuman VSIG4 protein [orb392708]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
Human cells
500 μg, 50 μg, 10 μgHuman VSIG4 ELISA Kit [orb405547]
Human
31.25 pg/mL-2000 pg/mL
7.81 pg/mL
10 x 96 t, 5 x 96 t, 96 t, 48 t, 24THuman VSIG4 Protein [orb1476714]
Greater than 95% as determined by SDS-PAGE.
30.6 kDa
Mammalian cell
20 μg, 100 μg, 1 mg
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