Human S100A14 Protein

• Catalog Number: orb257816
• Category: Proteins
• Description: Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 12.5 kDa
• Target: S100A14
• Protein Sequence: AAH05019
• Source: Human S100A14, His Tag (orb257816) is expressed from E.coli cells. It contains AA Met 1 - His 104 (Accession # Q9HCY8-1).
• Expression System: E. coli
• Expression Region: Met 1 - His 104
• Endotoxins: 1.0 EU per μg
• NCBI: AAH05019
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, 150 mM NaCl, pH8.0
• Alternative names: S100A14,S114,S100A15
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human S100A14 protein