Clusterin Antibody / Apolipoprotein J / APO-J

• Catalog Number: orb1716280
• Category: Antibodies
• Description: Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, -Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: CLU/4724
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: A portion of amino acids 150-300 from the human CLU protein was used as the immunogen for the Clusterin antibody.
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml
• Conjugation: Unconjugated
• Formula: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Hazard Information: This Clusterin antibody is available for research use only.
• UniProt ID: P10909
• Storage: Aliquot the Clusterin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Application notes: Optimal dilution of the Clusterin antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.