CD45 antibody

• Catalog Number: orb758802
• Category: Antibodies
• Description: Rat monoclonal antibody to CD45
• Species/Host: Rat
• Clonality: Monoclonal
• Clone Number: RA3-6B2
• Tested applications: FC, IF, IHC
• Reactivity: Mouse
• Isotype: IgG2a
• Immunogen: This antibody was raised in Lou-M rats using a popliteal lymph node immunisation and fusion protocol as described by Martiniello et al (1994)
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CD45R
• UniProt ID: P06800
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: B220; CD45; CD45 antigen; Cluster designation 45R;
• Note: For research use only
• Application notes: This antibody has been used in FACS analyses, immunoprecipitation, immunoblotting, and immunohistochemistry in various studies, such as to understand the role of PD-1 in maintaining islet-specific tolerance in type 1 diabetes (Martinov et al, 2016), to investigate how Staphylococcus aureus enterotoxins spread systemically and trigger inflammatory cascades (Svedova et al, 2016), to highlight the physiologic importance of cell-type specific balancing of AhR/AhRR expression in response to microbial, nutritional and other environmental stimuli (Brandstätter et al, 2016), and to examine the role of FBXW7 in suppression of cancer metastasis in a non-cell-autonomous manner (Yumimoto et al, 2015).
• Expiration Date: 12 months from date of receipt.