CD40 antibody

• Catalog Number: orb613917
• Category: Antibodies
• Description: Rabbit monoclonal antibody to CD40
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: A54 scFv
• Tested applications: Blocking, ELISA
• Reactivity: Human
• Isotype: IgG
• Immunogen: A54 human anti-CD40 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcγ fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CD40
• UniProt ID: P25942
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: TNFRSF5; A54; Tumor necrosis factor receptor super
• Note: For research use only
• Application notes: A54 is able to block the CD40-CD154 interaction by around 60-80% and can also induce CD40 sinalling in human B cells when at 'unusually high concentrations' (The CD40 receptor - target, tool and technology, Ellmark, 2002). This scFv can also be used for ELISA studies (PMID: 12153507)
• Expiration Date: 12 months from date of receipt.