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    CD4 antibody

    CD4 antibody

    Catalog Number: orb348912

    DispatchUsually dispatched within 5-10 working days
    $ 531.00
    Catalog Numberorb348912
    CategoryAntibodies
    DescriptionRabbit monoclonal antibody to CD4
    Species/HostMouse
    ClonalityMonoclonal
    Clone NumberMT310
    Tested applicationsFC, IF, IHC-P, IP, WB
    ReactivityHuman, Primate
    IsotypeIgG
    Concentration1 mg/ml
    PurityPurified
    ConjugationUnconjugated
    TargetCD4
    UniProt IDP01730
    StorageStore at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
    Buffer/PreservativesPBS with 0.02% Proclin 300.
    Alternative namesLeu3/T3; T-cell differentiation antigen; Ly-4; L3T
    Read more...
    NoteFor research use only
    Application notesmt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10.
    Expiration Date12 months from date of receipt.

    Herzog, C. et al. Monoclonal anti-CD4 in arthritis Lancet, 2, 1461-1462 (1987)

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